REWIRE: Rapid brain plasticity in humans and rodents with high-resolution MRI

This project aims to investigate the time-course, maintenance, and individual predictors of brain plasticity when learning a new motor task. Repeated structural scanning of the brain with ultra-high resolution MRI at 7 Tesla and 9.4 Tesla will be carried out, respectively, on humans and mice, learning a new motor task. This project will shed light on the mechanisms behind rapid plasticity in the human brain, with implications for cognitive interventions and rehabilitation therapies across the lifespan.

Principal Investigator: Dr. Gaia Olivo. LEaP Lab members: Gaia Olivo, Daniel Marcellino, Sean Cully, practicum master’s students.

Project Updates

2024.12.17. Ethical application for the preclinical experiments submitted for approval by the Etikprövningsmyndigheten.

2024.10.02. First LEaP Lab kick-off meeting. Welcome to our six practicum students!

2024.09.30. Scanning of human participants approved by the 7 Tesla National Facility, part of the Lunds Biomedical Imaging Center (LBIC).

2024.09.10. Ethical permit for the human experiments granted by the Etikprövningsmyndigheten.

2024.08.19. New PhD student on board. Welcome to Sean Arthur Cully!

2024.07.01. New senior researcher on board. Welcome to Dr. Daniel Marcellino!

2023.11.28. Wallenberg Academy Fellowship (WAF) 2023. Grant number: 2023.0024. Amount awarded: 9,000,000 sek. Period: 5 years (2024 - 2029). Title of Project: “Re-wiring the brain: examining the dynamics of rapid brain plasticity in humans and rodents with high-resolution MRI”. Founded by the Knut and Alice Wallenberg Foundation.